Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review.

Purpose of review

To summarise the evidence regarding which patients might benefit from deprescribing antihypertensive medications.

Recent findings

Older patients with frailty, multi-morbidity and subsequent polypharmacy are at higher risk of adverse events from antihypertensive treatment, and therefore may benefit from antihypertensive deprescribing. It is possible to examine an individual’s risk of these adverse events, and use this to identify those people where the benefits of treatment may be outweighed by the harms. While such patients might be considered for deprescribing, the long-term effects of this treatment strategy remain unclear. Evidence now exists to support identification of those who are at risk of adverse events from antihypertensive treatment. These patients could be targeted for deprescribing interventions, although the long-term benefits and harms of this approach are unclear.

Perspectives

Randomised controlled trials are still needed to examine the long-term effects of deprescribing in high-risk patients with frailty and multi-morbidity.

© 2024. The Author(s).

Overzicht publicatie

TitelStrategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review.
Datum2 februari 2024
Tijdschrift naamCurrent hypertension reports
Tijdschrift nummerpubmed:38305846
DOI10.1007/s11906-024-01293-5
PubMed38305846
AuteursSheppard JP, Benetos A, Bogaerts J, Gnjidic D & McManus RJ
TrefwoordenAging, Drug-related side effects and adverse reactions, Frailty, Hypertension, Multi-morbidity, Polypharmacy, Risk prediction
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